Responded to @kasparsd:
@oivaeskola Are you planning on running HomeAssistant on macOS inside Virtualbox? In that case you can run the official MQTT broker add-on https://github.com/home-assistant/addons/blob/master/mosquitto/DOCS.md and MQTT component https://www.home-assistant.io/integrations/mqtt/ alongside the zigbee2mqtt add-on https://github.com/zigbee2mqtt/hassio-zigbee2mqtt#installation